Hemodynamics of Cerebral Aneurysm Initiation: The Role of Wall Shear Stress and Spatial Wall Shear Stress Gradient
نویسندگان
چکیده
منابع مشابه
Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient.
BACKGROUND AND PURPOSE Cerebral aneurysms are preferentially located at arterial curvatures and bifurcations that are exposed to major hemodynamic forces, increasingly implicated in the life cycle of aneurysms. By observing the natural history of aneurysm formation from its preaneurysm state, we aimed to examine the hemodynamic microenvironment related to aneurysm initiation at certain arterial...
متن کاملWall shear stress distribution inside growing cerebral aneurysm.
BACKGROUND AND PURPOSE Hemodynamic stimulation has been suggested to affect the growth of cerebral aneurysms. The present study examined the effects of intra-aneurysmal hemodynamics on aneurysm growth. MATERIALS AND METHODS Velocity profiles were measured for 2 cases of AcomA aneurysms. Realistically shaped models of these aneurysms were constructed, based on CT angiograms. Flow fields and WS...
متن کاملMagnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms.
BACKGROUND AND PURPOSE Wall shear stress (WSS) is one of the main pathogenic factors in the development of saccular cerebral aneurysms. The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD). METHODS Twenty mathematical models of MCA vessels with aneurysms were created by 3-dimensiona...
متن کاملAccuracy of MRI wall shear stress estimation
Methods Three methods for WSS estimation were studied. These methods are based on 1) linear extrapolation (LE) of MRI velocity data, 2) MRI velocity data in combination with estimation of location of vessel wall, and 3) Fourier velocity encoding (FVE). Numerical velocity fields representing axisymmetric 2D velocity profiles were generated for WSS values ranging from 1-20 N/m. Based on the numer...
متن کاملMechanical aspects of blood-wall interaction : wall shear stress measurement
The predilection of atherosclerotic lesions for specific sites in the arterial tree is believed to be related t o the wall shear stress, exerted by the blood flow. Measurement of the magnitude of the wall shear stress is difficult and is frequently determined by an extrapolation of the velocity field t o find the wall shear rate and an estimation of the viscosity of the fluid in the neighborhoo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2011
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a2339